Insulin-like growth factor-I (IGF-I) and IGF binding protein-5 in Schwann cell differentiation
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Insulin-like growth factor-I (IGF-I) and IGF binding protein-5 in Schwann cell differentiation.
Schwann cells (SCs) are the myelin producing cells of the peripheral nervous system. During development, SCs cease proliferation and differentiate into either a myelin-forming or non-myelin forming mature phenotype. We are interested in the role of insulin-like growth factor-I (IGF-I) in SC development. We have shown previously SCs proliferate in response to IGF-I in vitro. In the current study...
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ژورنال
عنوان ژورنال: Journal of Cellular Physiology
سال: 1997
ISSN: 0021-9541,1097-4652
DOI: 10.1002/(sici)1097-4652(199705)171:2<161::aid-jcp6>3.0.co;2-m